Products

Active ingredients

Greenpharma develops innovative active ingredients to respond to the customers’ needs in terms of naturality, efficient, safe and sustainable products.

We set highest scientific and technical standards to produce our products, with solid substantiations of their activities. Here you will find our portfolio of active ingredients.

HEALTHY AGING INGREDIENTS

BIOLOGICAL PROPERTIES
Atophylline Restores a healthy skin in Atopic Disorders and improves quality of life (clinically tested)
Centella asiatica organic extract (OCAE) Soothing, wound healing, increase elastin level
Centellane Liquid and stable version of OCAE
Dumaflorine Restores skin barrier function – improves dermal structure (clinically tested)
Hibamorine Protects formula, boosts preservative actions, anti-inflammatory and anti-ageing
Hinoline Protects formula, boosts preservative actions, increases the level of collagen 3 & hyaluronic acid, beneficial on atopic & acneic prone skins (clinically tested)
Poppyderm Increases the expression of hyaluronic acid in the skin and hydration
Primadulcine Lower cortisol rate, responsible fr the stress-induced aging

You can not find the product you need? We can help you to develop it, please see our section about Ingredient development or Brand development on demand.

Dumaflorine

DUMAFLORINE: a rejuvenating extract from black tulip flowers “Queen of the Night”

Proven efficiency (ex vivo):

  • Decrease the oxidative stress by 70%
  • Increase the thickness of the stratum corneum by 53% and dermis by 400%
  • Decrease the stratum corneum permeability by 50%

Applications:

  • Aging prevention
  • Strengthening of the barrier function

Suggested association:

Dumaflorine + Primadulcine to have both preventing and repairing anti-aging effects

 

Clinically tested: Read the article in J Cosmet Dermatol. 2020

Hinoline

HINOLINE: a 100 % natural preservative-like solution with multiple functions

Proven efficiency:

  • Formula protection
  • Preservative booster
  • Strong reduction of acne signs (Clinical evaluation)
  • Increase of collagen 3 level in normal and UVB irradiated skin (ex vivo)
  • Increase hyaluronic acid level in normal and UVB irradiated skin (ex vivo)

Applications:

  • Protection of formula
  • Booster of preservatives
  • Anti-aging
  • Acne-prone skin (clinically tested)

Suggested association :

Hinoline + Primadulcine for acne-prone skin: bacterial control and sebum reduction

Poppyderm

POPPYDERM : an original anti-aging from poppy flowers

Proven efficiency (ex vivo): 

  • Increases the expression of hyaluronic acid in epidermis by 19%
  • Increases the expression of hyaluronic acid in papillary dermis by 33%
  • Densification activity of the papillary dermis
  • Maintain good structure of the dermal-epidermal junction

Applications:

  • Anti-wrinkles: plumping effect
  • Skin hydration

ORGANIC CENTELLA ASIATICA EXTRACT (OCAE)

Centella asiatica is used in Chinese and Indian traditional medicine as a rejuvenating product and also in pharmaceutical applications. Its properties are well-documented in the scientific literature.

It has beneficial effects on skin and wound healing by improving a wide range of cutaneous parameters. These biological effects are mediated by triterpenes such as asiaticoside, madecassoside, asiatic acid and madecassic acid.

Centella being a very well-known plant in cosmetics, our extract is unique in 3 ways:

  • 100% organic
  • COSMOS certified
  • a high content in active compounds (asiaticoside & madecassoside)

These unique combined characteristics on the market make our active ingredient, a must-have product for organic industry.

Applications:

  • Anti-wrinkles
  • Soothing
  • Hydration
  • Skin detoxification

Centellane

CENTELLANE is an easy-to-formulate and stable liquid ingredient of Centella asiatica. The originality of this active ingredient is its stable and guaranteed content in active compounds. Both characteristics in a same product is unique on the market.

Primadulcine

PRIMADULCINE: a skin stress reliever from primrose

Primrose is a symbol of spring and of nature revival. The plant is used to calm mild anxiety and soothe skin irritation in French traditional medicine.

Proven efficiency:

  • Directly inhibits the cortisone-to-cortisol converting enzyme: 11β-hydroxysteroid dehydrogenase 1
  • Decrease cortisol in keratinocytes by 43%
  • Increase hyaluronic acid synthesis by 47%
  • Increase collagen III synthesis by 73% in presence of UVB (ex vivo)
  • Increase elastin synthesis by 74% in presence of UVB (ex vivo)

Applications:

  • Reduction of stress-induced aging
  • Skincare for oily and acne-prone skin

Suggested association:

  • Primadulcine + Hinoline for acne-prone skin: bacterial control and sebum reduction
  • Primadulcine + Dumaflorine to have both preventing and repairing anti-aging effects

Atophylline

Atophylline: a bioinspired skin care against atopic dermatitis (AD)

Based on an innovative concept of neutraligand, it acts selectively on chemokine CCL17 to block the vicious circle of AD.

Proven efficiency:

  • Inhibits the chemokine CCL17 and not its receptor
  • Inhibits genes involved in AD
  • Stimulates synthesis of collagen, elastin and hyaluronic acid in normal cells.

At the clinical level:

  • Reduces itchy skin, skin inflammation
  • Increases hydration and skin barrier function
  • Improves quality of life.

Tested clinically.

Hibamorine

Hibamorine: a bioinspired and biosourced pure compound from by-products of Aomori Hiba wood, the “Tree of Life”

Proven efficiency:

  • Formula protection
  • Preservative booster
  • Reduces inflammation via the decrease TNF-α, IL-6 and PGE2 expression
  • Anti-aging via sirtuin 1 pathway

Applications:

  • Protection of formula
  • Booster of preservatives
  • Anti-aging
  • Soothing

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